Bioinformatics for the reconstruction of the evolutionary path “We can use the DNA of contemporary species to reconstruct evolutionary events. Our genes were formed over eons of evolution. During that time they have changed dramatically, but still retain echoes of a distant past. ” Vosseberg adds:” We have a large amount of genetic material available from a variety of organisms, and we can use computers to reconstruct the evolution of thousands of genes, including those ancient gene duplications. These reconstructions have allowed us to uncover the timing of important intermediate steps. ” In the words of Berend Snel, from Utrecht University, also lead author of the study: “The scientists did not have a chronology of these events,

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but now we have managed to reconstruct a Bahrain WhatsApp Number List rough timeline.” To achieve this, the researchers adapted an existing method developed in the laboratory of Gabaldón to create a new protocol, which has resulted in new insights. These indicate that a great deal of complex cellular machinery had evolved even before symbiosis with mitochondria, including the development of transport within the cell and the cytoskeleton. ” The symbiosis was not an event that served as a catalyst for all the rest. We observed a spike in gene duplications much earlier, which indicates that the cellular complexity had already increased before that moment, “he says.Snel . “Our study suggests that the ancestral host that acquired the mitochondrial endosymbiont had

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already developed a certain complexity in terms of a dynamic cytoskeleton and membrane trafficking,” says Gabaldón . “This could have favored the establishment of symbiotic associations with other microorganisms, including the mitochondrial ancestor, which was finally integrated.” Reference article : Timing the origin of eukaryotic cellular complexity with ancient duplications. Julian Vosseberg, Jolien JE van Hooff, Marina Marcet-Houben, Anne van Vlimmeren, Leny M. van Wijk, Toni Gabaldón & Berend Snel. Nature Ecology & Evolution (2020). DOI: 10.1038 / s41559-020-01320-z Source: University of Utrecht About IRB Barcelona Created in 2005 by the Generalitat de Catalunya and the University of Barcelona, ​​IRB Barcelona has been the Severo Ochoa

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