The Paleogenomics study carried out by the Human Evolutionary Biology group of the Faculty of Science and Technology, led by Concepción de la Rua, in collaboration with researchers from Sweden, the Netherlands and Romania, has made it possible to recover, from two teeth , the complete sequence of the female mitogenome of Pestera Muierii (PM1). This mitochondrial genome corresponds to the basal U6 lineage, currently disappeared, and from which the U6 lineages now existing in North African populations basically descend. The study, therefore, has not only made it possible Argentina Email Database to confirm the Eurasian origin of the U6 lineage, but also to support the hypothesis that at the beginning of the Upper Paleolithic, some 40-45,000 years ago, some populations began a migration back to Africa from Eurasia.
The individual Pestera Muierii represents an offshoot of this journey back to Africa, for which there is no direct evidence due to the scarcity of Paleolithic fossil remains in North Africa. “At this moment, the research group is analyzing the nuclear genome, the results of which can provide us with information on its relationship with Neanderthals and on the existence of genomic variations associated with the immune system that explain the evolutionary success of Homo sapiens compared to other human species with which it coexisted. In addition, we will be able to know the phenotypes traits of the first Homo sapiens and the influence of the population movements of the past in the understanding of our evolutionary history “, explains Professor Concepción de la Rúa. Bibliographic reference M.
The mitogenome of a 35,000-year-old Homo sapiens from Europe supports a Palaeolithic back-migration to Africa. Scientific Reports DOI: 10.1038/srep25501in other related disciplines, such as Ecology, but they are not frequent in human evolution studies”, points out Ana Mateos.The genetic changes in the ‘peak’ still produce brightly fluorescent GFP, while those around the edges do not. “The fitness landscape is an abstract concept that simplifies our thinking of how the characteristics of an organism come from its underlying genetic makeup, Kondrashov explains. “This is the first time anyone has been able to generate real data to graphically represent this concept, looking at combinations of genetic changes rather than just single mutations.” Postdoctoral researcher Karen Sarkisyan, first author on the paper, says,