“Loss is nothing more than change, and change is a delight of nature,” says the quote from the philosopher and emperor Marcus Aurelius chosen to open the scientific article that reviews the phenomenon of gene loss and its impact on the evolution of living beings. The work, which has been published in the journal Nature Reviews Genetics, is signed by professors Ricard Albalat and Cristian Cañestro, from the Department of Genetics, Microbiology and Statistics and the Biodiversity Research Institute (IRBio ) of the University of Barcelona. This article has just been selected as one of the recommended works with the mention of teaching interest in genetics and genomics by the Faculty of 1000 Prime, an international ranking that identifies and re-evaluates the best articles on biology and medicine with the support of a scientific

community of more than 10,000 academics from around the world. Viewing the loss of a gene as an evolutionary force is a counterintuitive idea; it is easier to think that only Bahamas Email Lists when we win something — genes, in this case — can we evolve. But the new work by these authors, who are members of the Evolution and Development Research Group (EVO-DEVO) of the University of Barcelona, ​​reinforces the vision of gene loss as a process with enormous potential for genetic change and evolutionary adaptation. Losing genes is also an evolutionary engine A gene is lost when it is physically removed from the genome (by illegitimate recombination, rearrangement, etc.) or when it is still in the genome but is not functional due to a mutation (point changes, insertions, deletions, etc’

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The sequencing of the genomes of very diverse organisms has revealed that the loss of genes has been a frequent phenomenon during the evolution of all forms of life. In some cases, it has been shown that the loss can suppose an adaptive response to stressful situations in the face of sudden environmental changes “, explains Professor Cristian Cañestro. “In other cases,” continues the expert, “there are gene losses that, despite being neutral per se, have contributed to genetic and reproductive isolation between populations, and therefore, to speciation, or have participated in sexual differentiation by contribute to the formation of a new Y chromosome. The fact that the gene loss patterns are not stochastic, but there are biases in the missing genes (depending on the type of function of the

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