information on the genetic elements related to the formation of the knee. In addition, they have served to propose an evolutionary model of how the adaptation of the knee to bipedalism took place at the genetic level. This model describes how after a period of significant limitations to genetic variation aimed at favoring the most optimal morphological structure, the appearance of tolerable changes in development and early stages of life may have led to an increase in genetic vulnerability to osteoarthritis. The evolutionary model developed is an example of how complex diseases can emerge in parallel or later with other human adaptations. The researchers are confident that more advanced study animal models can provide ” effective and

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realistic tools for testing osteoarthritis treatments in the context of genetic and non-genetic risk factors .” The new genomic study compares several genetic variants associated with ADHD Ecuador Phone Number List described in current European populations to evaluate their evolution in modern and ancient human samples ( Homo sapiens ) and in archaic samples of Neanderthals ( Homo neanderthalensis ). According to the conclusions, the downward trend observed in European populations could not be explained either by genetic mixing with African populations or by the introgression of Neanderthal genomic segments into our genome. The research is directed by Bru Cormand, professor at the Faculty of Biology and member of the Institute of Biomedicine of the University of

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Barcelona (IBUB), the Sant Joan de Déu Research Institute (IRSJD) and the CIBER for Rare Diseases (CIBERER), and by researcher Òscar Lao, from the National Center for Genomic Analysis (CNAG), part of the Center for Genomic Regulation (CRG). Research groups from the University of Aarhus (Denmark) and from the State Medical University of New York, in the United States. ADHD: an adaptive value in the evolutionary lineage of humans? Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that can have a great impact on the lives of those affected. Characterized by hyperactivity, impulsivity, and attention deficit, it is very common in current populations — it has a prevalence of 5% in children

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