Center of Excellence since 2011. The objective of IRB Barcelona is to carry out research of excellence in biomedicine and improve people’s quality of life and, in In parallel, promote the training of talent, technology transfer and the social communication of science. The 27 laboratories and seven technology platforms work to answer basic questions in biology and oriented to diseases such as cancer, metastasis, Alzheimer’s, diabetes and rare diseases. It is an international center that welcomes around 400 workers of more than 30 nationalities. It is located in the Barcelona Science Park. The lack of some genes in the BEX / TCEAL cluster could be related to some alterations associated with autism spectrum disorder. This is clear from a
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preclinical study published in the journal Genome Belarus WhatsApp Number List Biology and directed by Professor Jordi Garcia Fernàndez, of the Faculty of Biology and the Institute of Biomedicine (IBUB) of the University of Barcelona, and the researcher Jaime Carvajal, of the Andalusian Center of Development Biology-Pablo de Olavide University (CSIC-UPO). The discovered genes are derived from transposons that are involved in complex neuronal functions and have not been investigated so far in the context of autism spectrum disorder and other neurological pathologies. The research, carried out with animal models, also describes some molecular mechanisms that are decisive in the development of the neocortex in humans and other placental mammals. Also
authors of the work are the UB experts Enrique Navas Pérez, Bru Cormand, Gemma Marfany, Serena Mirra, Noèlia Fernández Castillo, Ester Antón and Carlos Herrera (also members of the IBUB, IRSJD and CIBERER), and Eduardo Soriano and Fausto Ulloa (UBNeuro-CIBERNED), among others. Teams from the Pablo de Olavide University, the Center for Genomic Regulation (CRG), the Pompeu Fabra University, the University of Murcia, the Anton Dohrn Zoological Station in Naples (Italy) and the Carolina University (Czech Republic) also participate in the study. . Domestication of transposons: how can new functional genes originate? The BEX / TCEAL cluster is a little-studied gene family of fourteen genes located on the X chromosome.